000			03101cam a2200397 i 4500
001			81
008			141024s2011 cn ad 001 0 eng u
020			_a9780132064521 _q(hardback)
020			_a9780136121497 _q(hardback set)
020			_a9780137032105 _q(Mastering chemistry student access kit)
020			_a9780137032129 _q(study card)
040			_aTR-IsMEF _beng _erda _cTR-IsMEF
041	0		_aeng
049			_aTR-IsMEF
050	0	0	_aQD31.3 _b.P48 2011
100			_aPetrucci, Ralph H., _eauthor.
245			_aGeneral chemistry : _bprinciples and modern applications / _cRalph H. Petrucci, F. Geoffrey Herring, Jeffry D. Madura, Bissonnette Carey.
250			_aTenth edition.
264			_aToronto, Ont. : _bPearson Canada, _c2011.
300			_axxiv, 1303, [96] pages : _billustrations, charts ; _c29 cm. + _estudy card ([12] pages : color illustrations ; 28 cm.) + student access kit (23 cm.)
336			_atext _2rdacontent
337			_aunmediated _2rdamedia
338			_avolume _2rdacarrier
500			_aIncludes index.
500			_aPrevious ed.: Upper Saddle River, N.J. : Pearson Education, c2007.
500			_aSupplemet : General chemistry: principles and modern applications, 10e. Petrucci / Herring / Madura / Bissonnette Study Card. Prepared by Noel A. George.
520			_aThe Molecule on the Front Cover is Paclitaxel, C47H51NO14 a chemotherapy drug that has been successful in treating breast, lung, and ovatian cancer. It is extracted from the bark of the Pacific Yew tree (Taxus brevifolia). Unfortunately, the bark of a 100-year-old Pacific Yew tree yields about 3 kg of bark and only 300 mg of paclitaxel, barely enough for a single dose of the drug (Taxol). -- he synthesis of this molecule engaged the attention of chemists for more than 20 years until finally, in 1994, chemists from Florida State University and from the University of California (San Diego) announced independently that they were able to synthesize it from simpler and readily available starting materials. A major challenge in the synthesis of paclitaxel is getting the spatial arrangement of atoms around 11 of the carbon atoms just right. These 11 carbon atoms are identified in the ball-and-stick structure by green or purple circles. If the synthesis is not done carefully, up to 2048 different possible paclitaxel-like structures could be obtained, but only one is known to have the desired anti-tumor activity. Because chemists can now synthesize paclitaxel, it is possible for researchers to explore how it works and design new chemotherapeutic drugs that are safer and more effective. --Book Jacket.
650		0	_aChemistry
650		0	_aChemistry _vProblems, exercises, etc.
700	1		_aHerring, F. Geoffrey, _eauthor.
700	1		_aMadura, Jeffry D., _eauthor.
700	1		_aBissonnette, Carry, _eauthor.
900			_aMEF Üniversitesi Kütüphane katalog kayıtları RDA standartlarına uygun olarak üretilmektedir / MEF University Library Catalogue Records are Produced Compatible by RDA Rules
942			_2lcc _cBKS _05
999			_c983 _d983
003			KOHA