TY  - BOOK
AU  - Ye,Huilin
AU  - Shen,Zhiqiang
AU  - Li,Ying
ED  - Morgan & Claypool Publishers,
ED  - Institute of Physics (Great Britain),
TI  - Multiscale modeling of vascular dynamics of micro- and nano-particles: application to drug delivery system 
T2  - [IOP release 6]
SN  - 9781643277929
AV  - RM301.63 .Y456 2019eb
U1  - 615.7 23
PY  - 2019///]
CY  - San Rafael [California] (40 Oak Drive, San Rafael, CA, 94903, USA)
PB  - Morgan & Claypool Publishers
KW  - Drug targeting
KW  - Drug carriers (Pharmacy)
KW  - Nanoparticles
KW  - Therapeutic use
KW  - Blood-vessels
KW  - Biomechanics
KW  - Biomedical materials
KW  - Mechanical properties
KW  - Multiscale modeling
KW  - Drug Delivery Systems
KW  - Drug Carriers
KW  - therapeutic use
KW  - Blood Vessels
KW  - physiology
KW  - Biocompatible Materials
KW  - Biomechanical Phenomena
KW  - Models, Anatomic
KW  - Models, Biological
KW  - Biophysics
KW  - bicssc
KW  - SCIENCE / Life Sciences / Biophysics
KW  - bisacsh
N1  - "Version: 20191201"--Title page verso; "A Morgan & Claypool publication as part of IOP Concise Physics"--Title page verso; Includes bibliographical references; 1. Background -- 1.1. Blood flow in human vasculature -- 1.2. Vascular targeting and margination of particles in blood flow -- 1.3. Adhesion of particles on endothelium wall; part I. Numerical method -- 2. Numerical methods: fluid-structure interaction and adhesive dynamics -- 2.1. Fluid-structure interaction -- 2.2. Adhesive dynamics -- 2.3. Validation of numerical method; part II. Applications -- 3. Anomalous vascular dynamics of nanoworms within blood flow -- 3.1. Motivation -- 3.2. Experimental and computational results; 4. Adhesion behavior of a single cell on the endothelial wall -- 4.1. Introduction -- 4.2. Computational model -- 4.3. Results and discussion; 5. Localization of soft particles: margination and adhesion -- 5.1. Introduction -- 5.2. Physical problem and computational method -- 5.3. Results and discussion; 6. Shape-dependent transport of micro-particles in blood flow: from margination to adhesion -- 6.1. Introduction -- 6.2. Computational model setup -- 6.3. Results and discussion; 7. Conclusion and perspective -- Appendix A. Coarse-grained potential for RBCs; Professional and scholarly; Also available in print
N2  - Recent advances in this exciting field see the potential to employ nanomedicine and game-changing methods to deliver drug molecules directly to diseased sites. To optimize and then enhance efficacy and specificity, the control and guidance of dr
UR  - https://ezproxy.mef.edu.tr/login?url=https://iopscience.iop.org/book/978-1-64327-792-9
ER  -