Ye, Huilin  (Mechanical engineer), <br/><br/>
Multiscale modeling of vascular dynamics of micro- and nano-particles :  application to drug delivery system / 
Huilin Ye, Zhiqiang Shen and Ying Li. 
 - 1 online resource (various pagings) :  illustrations (some color). 
 - [IOP release 6] IOP concise physics,  2053-2571 .
 - IOP (Series).  Release 6. IOP concise physics. .
<br/><br/> "Version: 20191201"--Title page verso.  "A Morgan & Claypool publication as part of IOP Concise Physics"--Title page verso. 
<br/><br/>Includes bibliographical references. 
<br/><br/>1. Background -- 1.1. Blood flow in human vasculature -- 1.2. Vascular targeting and margination of particles in blood flow -- 1.3. Adhesion of particles on endothelium wall part I. Numerical method -- 2. Numerical methods: fluid-structure interaction and adhesive dynamics -- 2.1. Fluid-structure interaction -- 2.2. Adhesive dynamics -- 2.3. Validation of numerical method part II. Applications -- 3. Anomalous vascular dynamics of nanoworms within blood flow -- 3.1. Motivation -- 3.2. Experimental and computational results 4. Adhesion behavior of a single cell on the endothelial wall -- 4.1. Introduction -- 4.2. Computational model -- 4.3. Results and discussion 5. Localization of soft particles: margination and adhesion -- 5.1. Introduction -- 5.2. Physical problem and computational method -- 5.3. Results and discussion 6. Shape-dependent transport of micro-particles in blood flow: from margination to adhesion -- 6.1. Introduction -- 6.2. Computational model setup -- 6.3. Results and discussion 7. Conclusion and perspective -- Appendix A. Coarse-grained potential for RBCs. 
<br/><br/> Recent advances in this exciting field see the potential to employ nanomedicine and game-changing methods to deliver drug molecules directly to diseased sites. To optimize and then enhance efficacy and specificity, the control and guidance of dr 
<br/><br/> Professional and scholarly. 
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<br/><br/><br/>Mode of access: World Wide Web. <br/>System requirements: Adobe Acrobat Reader, EPUB reader, or Kindle reader. 
<br/><br/><br/>Huilin Ye is a Ph.D. candidate in Mechanical Engineering at the University of Connecticut. His research interest is mainly on developing high-fidelity computational methods in biosystems, especially for the blood flow. The key tasks include two  
<br/><br/><label>ISBN: </label>9781643277929 9781643277905 
<br/><br/><label>Standard No.: </label>10.1088/2053-2571/ab4124  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Drug targeting.<br/>Drug carriers (Pharmacy)<br/>Nanoparticles--Therapeutic use.<br/>Blood-vessels.<br/>Biomechanics.<br/>Biomedical materials--Mechanical properties.<br/>Multiscale modeling.<br/>Drug Delivery Systems.<br/>Drug Carriers.<br/>Nanoparticles--therapeutic use.<br/>Blood Vessels--physiology.<br/>Biocompatible Materials.<br/>Biomechanical Phenomena.<br/>Models, Anatomic.<br/>Models, Biological.<br/>Biophysics.<br/>SCIENCE / Life Sciences / Biophysics.
<br/><br/><label>LC Class. No.: </label>RM301.63  / .Y456 2019eb 
<br/><br/><label>Dewey Class. No.: </label>615.7 
<br/><br/><label>National Library of Medicine Call No.: </label>QV 785  / Y37m 2019eb