TY  - BOOK
AU  - Mierke,Claudia Tanja
ED  - Institute of Physics, IOP - EBA (Great Britain),
TI  - Physics of cancer
T2  - [IOP release 5]
SN  - 9780750321174
AV  - RC262 .M547 2018eb vol. 2
U1  - 616.994 23
PY  - 2018///]
CY  - Bristol [England] (Temple Circus, Temple Way, Bristol BS1 6HG, UK)
PB  - IOP Publishing
KW  - Cancer cells
KW  - Mechanical properties
KW  - Cancer
KW  - Biophysics
KW  - Pathology, Molecular
KW  - Cell Transformation, Neoplastic
KW  - Cell Physiological Phenomena
KW  - Tumor Microenvironment
KW  - Biomechanical Phenomena
KW  - bicssc
KW  - SCIENCE / Life Sciences / Biophysics
KW  - bisacsh
N1  - "Version: 20181001"--Title page verso; Includes bibliographical references; part IV. The effect of microtubules and the mechanical properties of the nucleus on matrix invasion -- 9. Microtubules during migration and matrix invasion -- 9.1. The structure and assembly of microtubules -- 9.2. The assembly of the mitotic sp; 10. Nuclear deformability during migration and matrix invasion -- 10.1. The physical role of the nucleus in cell migration -- 10.2. Mechanical properties of the nucleus -- 10.3. Nucleus-cytoskeleton-extracellular matrix connections -- 10.4. Mech; part V. The impact of the tumor microenvironment on cellular invasion -- 11. The mechanical and structural properties of the microenvironment -- 11.1. Why is the extracellular matrix of connective tissue crucial for the invasion of cancer cells?; 12. The impact of cells and substances within the extracellular matrix tissue on mechanical properties and cell invasion -- 12.1. The impact of tumor-associated fibroblasts on matrix mechanical properties -- 12.2. Cancer-associated fibroblasts a; 13. The active role of the tumor stroma in regulating cell invasion -- 13.1. The stroma enhances malignant cancer progression -- 13.2. Biomechanical alterations in cancer cells -- 13.3. Extracellular matrix evoked alterations in cancer cell func; part VI. The impact of the mechanical and biochemical interaction of cancer cells with other cells in transendothelial migration -- 14. The impact of the mechanical and biochemical interaction of cancer cells with other cells in transendothelial; 15. The mechanical properties of endothelial cells altered by aggressive cancer cells -- 15.1. The role of endothelial cell stiffness -- 15.2. The role of the endothelial contractile apparatus -- 15.3. Interaction between cancer cells and endoth; 16. The role of macrophages during cancer cell transendothelial migration -- 16.1. What is the role of macrophages during cancer disease? -- 16.2. Impact of Mena on cancer cell invasion and macrophages -- 16.3. Impact of Mena on macrophages -- 1; Universities, students, PhDs, Post-Docs, Professors and researchers; Also available in print
N2  - In order to increase the healing opportunities of cancer, it is important to impair the dissemination and the spreading of cancer cells from the initial tumor and the formation of metastases in other organs or tissues of the human body. The unde
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ER  -