Foundations of regenerative biology and medicine / David L. Stocum.

By: Stocum, David L [author.]Contributor(s): Institute of Physics, IOP - EBA (Great Britain) [publisher.]Material type: TextTextSeries: IOP (Series)Release 5 | IOP expanding physicsPublisher: Bristol [England] (Temple Circus, Temple Way, Bristol BS1 6HG, UK) : IOP Publishing, [2018]Description: 1 online resource (various pagings) : illustrations (some color)Content type: text Media type: electronic Carrier type: online resourceISBN: 9780750316262 ebookSubject(s): Regenerative medicine | Tissue engineering | Regenerative Medicine | Tissue Engineering | Biomedical engineering | TECHNOLOGY & ENGINEERING / BiomedicalAdditional physical formats: Print version:: No titleDDC classification: 610. 28 LOC classification: QH499 .S764 2018ebNLM classification: WO 515Online resources: e-book Full-text access Also available in print.
Contents:
part I. Regenerative biology. 1. Regeneration -- 1.1. Introduction -- 1.2. Who and what regenerates? -- 1.3. A brief history of regenerative biology -- 1.4. The regenerative niche -- 1.5. Approaches to the study of regeneration -- 1.6. Mechanism
2. Wound repair by fibrosis -- 2.1. Fibrosis is studied primarily in skin -- 2.2. Structure and function of skin -- 2.3. Types of wounds -- 2.4. Stages of repair in acute wounds -- 2.5. Aging reduces the repair capacity of acute skin wounds -- 2
3. Regeneration by adult stem cells -- 3.1. Epithelial stem cells -- 3.2. Mesenchymal stem cells -- 3.3. Stem cells in non-regenerating organs
4. Non-stem cell regenerative mechanisms -- 4.1. Cellular re-growth: axon regeneration -- 4.2. Regeneration from pre-existing differentiated cells -- 4.3. Transdifferentiation: newt lens and retina
5. Appendage regeneration -- 5.1. Limb regeneration in urodele amphibians -- 5.2. Appendage regeneration in Xenopus -- 5.3. Mouse digit tip regeneration -- 5.4. Regeneration of mouse ear tissue -- 5.5. Regeneration of deer antlers -- 5.6. Enhanc
part II. Regenerative medicine. 6. Strategies of regenerative medicine -- 6.1. Historical notes -- 6.2. Biomimetic devices and organ transplants -- 6.3. Pharmaceutical induction of regeneration in situ -- 6.4. Cell transplants -- 6.5. Biomimetic
7. Pharmaceutical therapies for wound repair and regeneration -- 7.1. Skin -- 7.2. Neural tissues -- 7.3. Musculoskeletal tissues -- 7.4. Cardiac muscle
8. Cell transplants as regenerative therapy -- 8.1. Skin -- 8.2. Neural tissues -- 8.3. Liver and pancreas -- 8.4. Musculoskeletal tissues -- 8.5. Cardiac tissues -- 8.6. Hematopoietic deficiency disorders
9. Biomimetic tissues and organs -- 9.1. Skin -- 9.2. Muscle -- 9.3. Bone -- 9.4. Articular cartilage -- 9.5. Cardiovascular tissue -- 9.6. Liver and pancreas -- 9.7. Airways -- 9.8. Kidney and bladder
10. Into the adjacent possible -- 10.1. Technical innovations -- 10.2. Applications of edge technologies -- 10.3. Bioethics in regenerative medicine -- 10.4. Concluding statement.
Abstract: Regenerative biology and medicine is a rapidly developing field that can revolutionize medicine. It is a nexus of convergent science, drawing from chemistry, physics, mathematics and bioengineering. Foundations of Regenerative Biology and Medici

"Version: 20181001"--Title page verso.

Includes bibliographical references.

part I. Regenerative biology. 1. Regeneration -- 1.1. Introduction -- 1.2. Who and what regenerates? -- 1.3. A brief history of regenerative biology -- 1.4. The regenerative niche -- 1.5. Approaches to the study of regeneration -- 1.6. Mechanism

2. Wound repair by fibrosis -- 2.1. Fibrosis is studied primarily in skin -- 2.2. Structure and function of skin -- 2.3. Types of wounds -- 2.4. Stages of repair in acute wounds -- 2.5. Aging reduces the repair capacity of acute skin wounds -- 2

3. Regeneration by adult stem cells -- 3.1. Epithelial stem cells -- 3.2. Mesenchymal stem cells -- 3.3. Stem cells in non-regenerating organs

4. Non-stem cell regenerative mechanisms -- 4.1. Cellular re-growth: axon regeneration -- 4.2. Regeneration from pre-existing differentiated cells -- 4.3. Transdifferentiation: newt lens and retina

5. Appendage regeneration -- 5.1. Limb regeneration in urodele amphibians -- 5.2. Appendage regeneration in Xenopus -- 5.3. Mouse digit tip regeneration -- 5.4. Regeneration of mouse ear tissue -- 5.5. Regeneration of deer antlers -- 5.6. Enhanc

part II. Regenerative medicine. 6. Strategies of regenerative medicine -- 6.1. Historical notes -- 6.2. Biomimetic devices and organ transplants -- 6.3. Pharmaceutical induction of regeneration in situ -- 6.4. Cell transplants -- 6.5. Biomimetic

7. Pharmaceutical therapies for wound repair and regeneration -- 7.1. Skin -- 7.2. Neural tissues -- 7.3. Musculoskeletal tissues -- 7.4. Cardiac muscle

8. Cell transplants as regenerative therapy -- 8.1. Skin -- 8.2. Neural tissues -- 8.3. Liver and pancreas -- 8.4. Musculoskeletal tissues -- 8.5. Cardiac tissues -- 8.6. Hematopoietic deficiency disorders

9. Biomimetic tissues and organs -- 9.1. Skin -- 9.2. Muscle -- 9.3. Bone -- 9.4. Articular cartilage -- 9.5. Cardiovascular tissue -- 9.6. Liver and pancreas -- 9.7. Airways -- 9.8. Kidney and bladder

10. Into the adjacent possible -- 10.1. Technical innovations -- 10.2. Applications of edge technologies -- 10.3. Bioethics in regenerative medicine -- 10.4. Concluding statement.

Regenerative biology and medicine is a rapidly developing field that can revolutionize medicine. It is a nexus of convergent science, drawing from chemistry, physics, mathematics and bioengineering. Foundations of Regenerative Biology and Medici

Advanced undergraduate biology majors, beginning biology graduate students, chemistry, physics or bioengineering students.

Also available in print.

Mode of access: World Wide Web.

System requirements: Adobe Acrobat Reader, EPUB reader, or Kindle reader.

David L Stocum is Emeritus Professor of Biology and Emeritus Dean of the School of Science at Indiana University-Purdue University Indianapolis. He holds undergraduate degrees in Biology and Psychology from Susquehanna University, a MS in Zoolog

Title from PDF title page (viewed on November 8, 2018).